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  • RR-Src (trifluoroacetate salt)
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RR-Src (trifluoroacetate salt)

A synthetic peptide substrate

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RR-Src (trifluoroacetate salt)的二维码
  • 库存: 现货
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  • 500ug
    ¥1012.00
    810.00
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  • 1mg
    ¥1925.00
    1540.00
    - +
  • 5mg
    ¥6550.00
    5240.00
    - +
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  • 货号: ajcx23840
  • CAS: N/A
  • 别名: Arg-Arg-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly, RRLIEDAEYAARG, Src-Peptide
  • 分子式: C64H106N22O21?XCF3COOH
  • 分子量: 1519.7
  • 纯度: >98%
  • 溶解度: DMSO: 1 mg/ml,PBS (pH 7.2): 10 mg/ml
  • 储存: -20°C
  • 库存: 现货

Background

RR-Src is a synthetic peptide substrate that corresponds to the sequence in Src surrounding the tyrosine subject to phosphorylation.1,2 It is a substrate for EGF-mediated tyrosine phosphorylation.3 RR-Src inhibits IL-2-induced proliferation of cytotoxic T cells.4



1.Casnellie, J.E., Harrison, M.L., Pike, L.J., et al.Phosphorylation of synthetic peptides by a tyrosine protein kinase from the particulate fraction of a lymphoma cell lineProc. Natl. Acad. Sci. USA79(2)282-286(1982) 2.Pike, L.J., Gallis, B., Casnellie, J.E., et al.Epidermal growth factor stimulates the phosphorylation of synthetic tyrosine-containing peptides by A431 cell membranesProc. Natl. Acad. Sci. USA79(5)1443-1447(1982) 3.Cassel, D., Pike, L.J., Grant, G.A., et al.Interaction of epidermal growth factor-dependent protein kinase with endogenous membrane proteins and soluble peptide substrateJ. Biol. Chem.258(5)2945-2950(1983) 4.Taffs, R.E., and Sitkovsky, M.V.Modulation of the effector functions of cytolytic T-lymphocytes with synthetic peptide inhibitors of protein kinasesJ. Pharm. Sci.81(1)37-44(1992)

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