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- Angiotensin Receptor
- Saralasin (trifluoroacetate salt)
Saralasin (trifluoroacetate salt)
A peptide AT2 receptor agonist
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包装价格促销价数量
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5mg￥1337.001070.00- +
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10mg￥2425.001940.00- +
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25mg￥5337.004270.00- +
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50mg￥9337.007470.00- +
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- 货号: ajcx23876
- CAS: N/A
- 别名: Aralasin, 1-Sar-8-Ala-Angiotensin II
- 分子式: C42H65N13O10?XCF3COOH
- 分子量: 912.1
- 纯度: ＞98%
- 溶解度: DMSO: 5 mg/ml,PBS (pH 7.2): 10 mg/ml
- 储存: -20°C
- 库存: 现货
Background
Saralasin is a peptide angiotensin II type 2 (AT2) receptor agonist.1 It binds to AT2 receptors (Ki = 0.38 nM) and induces neurite outgrowth in NG108-15 cells when used at a concentration at 100 nM, an effect that can be inhibited by the AT2 receptor antagonist PD 123310. Saralasin (5 µg/animal, i.c.v.) enhances acquisition of the conditioned avoidance response in rats.2
1.Guimond, M.-O., Hallberg, M., Gallo-Payet, N., et al.Saralasin and sarile are AT2 receptor agonistsACS Med. Chem. Lett.5(10)1129-1132(2014) 2.Wright, J.W., and Harding, J.W.Brain angiotensin receptor subtypes AT1, AT2, and AT4 and their functionsRegul. Pept.59(3)269-295(1995)
