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  • Bottromycin A2
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Bottromycin A2

An antibiotic

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Bottromycin A2的二维码
  • 库存: 现货
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  • 包装
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  • 1mg
    ¥12700.00
    10160.00
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  • 货号: ajcx23904
  • CAS: 15005-62-6
  • 别名:
  • 分子式: C42H62N8O7S
  • 分子量: 823.1
  • 纯度: >98%
  • 溶解度: Ether: soluble,Methanol: soluble,Water: soluble
  • 储存: -20°C
  • 库存: 现货

Background

Bottromycin A2 is an antibiotic originally isolated from Streptomyces.1 It blocks the binding of aminoacyl-tRNA to the A site of the 50S ribosome, inhibiting protein synthesis.2 Bottromycin A2 is active against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci with MIC values of 1 and 0.5 µg/ml, respectively.



1.Nakamura, S., Yajima, T., Lin, Y., et al.Isolation and characterization of bottromycins A2, B2, C2J. Antibiot. (Tokyo)20(1)1-5(1967) 2.Gouda, H., Kobayashi, Y., Yamada, T., et al.Three-dimensional solution structure of bottromycin A2: A potent antibiotic active against methicillin-resistant Staphylococcus aureus and vancomycin-resistant EnterococciChem. Pharm. Bull. (Tokyo)60(2)169-171(2012)

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