Taurocholic Acid 3-sulfate (sodium salt)

A metabolite of taurocholic acid

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库存: 现货

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数量
500ug

￥600.00

480.00

- +
1mg

￥1150.00

920.00

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5mg

￥4762.00

3810.00

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10mg

￥8337.00

6670.00

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货号: ajcx23968
CAS: 71781-33-4
别名: 3-Sulfocholyl Taurine, TCA3S
分子式: C26H43NO10S2?2Na
分子量: 639.7
纯度: >98%
溶解度: DMF: 1 mg/ml,DMSO: 0.3 mg/ml,PBS (pH 7.2): 1 mg/ml
储存: -20°C
库存: 现货

Background

Taurocholic acid 3-sulfate (TCA3S) is a metabolite of the conjugated bile acid taurocholic acid .¹ Plasma levels of TCA3S are elevated in wild-type and Sortilin 1 (Sort1) knockout mice at 6 hours following bile duct ligation (BDL) and are further elevated in Sort1 knockout mice at 24 hours post-BDL.²

1.Lefebvre, P., Cariou, B., Lien, F., et al.Role of bile acids and bile acid receptors in metabolic regulationPhysiol. Rev.89(1)147-191(2009) 2.Li, J., Woolbright, B.L., Zhao, W., et al.Sortilin 1 loss-of-function protects against cholestatic liver injury by attenuating hepatic bile acid accumulation in bile duct ligated miceToxicol. Sci.161(1)34-47(2018)