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  • Ac-DEVD-CMK (trifluoroacetate salt)
Ac-DEVD-CMK (trifluoroacetate salt)的可视化放大

Ac-DEVD-CMK (trifluoroacetate salt)

An inhibitor of caspase-3

原价
¥1425-6375
价格
1140-5100
Ac-DEVD-CMK (trifluoroacetate salt)的二维码

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  • 货号: ajcx24028
  • CAS: N/A
  • 别名: AcAspGluValAspCMK, Caspase3 Inhibitor III
  • 分子式: C21H31ClN4O11?XCF3COOH
  • 分子量: 551
  • 纯度: >98%
  • 溶解度: DMSO: 50 mg/ml
  • 储存: -20°C
  • 库存: 现货

Background

Ac-DEVD-CMK is a cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, -7, -8, and -10.1,2,3 It is commonly used at concentrations up to 100 μM to examine the role of caspase-3-dependent apoptosis in biological systems.4,1



1.Mocanu, M.M., Baxter, G.F., and Yellon, D.M.Caspase inhibition and limitation of myocardial infarct size: Protection against lethal reperfusion injuryBritish Journal of Pharmacology130(2)197-200(2000) 2.Schrantz, N., Blanchard, D.A., Mitenne, F., et al.Manganese induces apoptosis of human B cells: Caspase-dependent cell death blocked by Bcl-2Cell Death and Differentiation6(5)445-453(1999) 3.Thornberry, N.A., and Lazebnik, Y.Caspases: Enemies withinScience2811312-1316(1998) 4.Zhang, Y., Wang, H., Li, J., et al.Peroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activationJournal of Neuroscience24(47)10616-10627(2004)

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