4'-Acetylchrysomycin B
A bacterial metabolite with antibacterial and anticancer activities
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包装价格促销价数量
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500ug￥3412.002730.00- +
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2.5mg￥12587.0010070.00- +
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- 货号: ajcx24040
- CAS: N/A
- 别名:
- 分子式: C29H30O10
- 分子量: 538.6
- 纯度: ＞98%
- 溶解度: DMSO: soluble,Methanol: soluble
- 储存: -20°C
- 库存: 现货
Background
4'-Acetylchrysomycin B is a bacterial metabolite and derivative of chrysomycin B that has been found in Streptomyces and has antibacterial and anticancer activities.1 It is active against strains of B. subtilis, B. cereus, Corynebacterium bovis, and E. faecalis (MICs = 2-64 µg/ml). 4'-Acetylchrysomycin B is cytotoxic against a panel of human cancer cell lines, including doxorubicin-sensitive or -resistant cells (IC50s = 1.7-14 and 260-370 ng/ml, respectively).
1.Wada, S.-I., Sawa, R., Iwanami, F., et al.Structures and biological activities of novel 4'-acetylated analogs of chrysomycins A and BJ. Antibiot. (Tokyo)70(11)1078-1082(2017)
