2-O-methyl PAF C-18 (hydrate)

A synthetic PAF analog

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库存: 现货

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5mg

￥875.00

700.00

- +
10mg

￥1650.00

1320.00

- +
50mg

￥6900.00

5520.00

- +
100mg

￥11725.00

9380.00

- +

已选 0 种 0 瓶

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货号: ajcx24068
CAS: N/A
别名: Edelfosine, ET-18-OCH3, 1Ooctadecyl2Omethyl<span ＞sn</span＞glyceryl3phosphorylcholine
分子式: C27H58NO6P?XH2O
分子量: 523.7
纯度: ＞98%
溶解度: PBS pH 7.2: ＞4.5 mg/ml (from Lyso-PAF C-18
储存: -20°C
库存: 现货

Background

2-O-methyl-PAF C-18 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. It has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart.¹ In rat astrocytes, 2-O-methyl PAF C-18 causes the release of large quantities of nitric oxide by a pathway involving activation of nitric oxide synthase.²

1.van Blitterswijk, W.J., Hilkmann, H., and Storme, G.A.Accumulation of an alkyl lysophospholipid in tumor cell membranes affects membrane fluidity and tumor cell invasionLipids22(11)820-823(1987) 2.Cardile, V., Jiang, X., Renis, M., et al.Effects of ether lipid 1-O-octadecyl-2-methoxy-rac-glycero-3-phosphocholine and its analogs PAF and CPAF on the release of nitric oxide in primary cultures of rat astrocytesBrain Research715(1-2)98-103(1996)

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生命科学

有机化学

无机化学

材料科学

2-O-methyl PAF C-18 (hydrate)

2-O-methyl PAF C-18 (hydrate)详情

Background

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