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  • 2-O-methyl PAF C-18 (hydrate)
2-O-methyl PAF C-18 (hydrate)的可视化放大

2-O-methyl PAF C-18 (hydrate)

A synthetic PAF analog

原价
¥875-11725
价格
700-9380
2-O-methyl PAF C-18 (hydrate)的二维码

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  • 货号: ajcx24068
  • CAS: N/A
  • 别名: Edelfosine, ET-18-OCH3, 1Ooctadecyl2Omethyl<span >sn</span>glyceryl3phosphorylcholine
  • 分子式: C27H58NO6P?XH2O
  • 分子量: 523.7
  • 纯度: >98%
  • 溶解度: PBS pH 7.2: >4.5 mg/ml (from Lyso-PAF C-18
  • 储存: -20°C
  • 库存: 现货

Background

2-O-methyl-PAF C-18 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. It has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart.1 In rat astrocytes, 2-O-methyl PAF C-18 causes the release of large quantities of nitric oxide by a pathway involving activation of nitric oxide synthase.2



1.van Blitterswijk, W.J., Hilkmann, H., and Storme, G.A.Accumulation of an alkyl lysophospholipid in tumor cell membranes affects membrane fluidity and tumor cell invasionLipids22(11)820-823(1987) 2.Cardile, V., Jiang, X., Renis, M., et al.Effects of ether lipid 1-O-octadecyl-2-methoxy-rac-glycero-3-phosphocholine and its analogs PAF and CPAF on the release of nitric oxide in primary cultures of rat astrocytesBrain Research715(1-2)98-103(1996)

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