Z-(L-Arg)-AMC (hydrochloride)
A fluorogenic substrate for trypsin, cathepsin B, and cathepsin H
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包装价格促销价数量
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10mg￥1150.00920.00- +
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25mg￥1987.001590.00- +
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50mg￥3662.002930.00- +
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100mg￥6775.005420.00- +
- 货号: ajcx24110
- CAS: 70375-22-3
- 别名: Z-L-精氨酸-7-胺基-4-甲基香豆素盐酸盐
- 分子式: C24H27N5O5?HCl
- 分子量: 502
- 纯度: ＞98%
- 溶解度: DMF: 1 mg/ml,DMSO: 1 mg/ml
- 储存: -20°C
- 库存: 现货
Background
Z-(L-Arg)-AMC is a fluorogenic substrate for trypsin, cathepsin B, and cathepsin H.1,2 Upon enzymatic cleavage by trypsin, cathepsin B, or cathepsin H, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify trypsin, cathepsin B, and cathepsin H activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
1.Zimmerman, M., Ashe, B., Yurewicz, E.C., et al.Sensitive assays for trypsin, elastase, and chymotrypsin using new fluorogenic substratesAnal. Biochem.78(1)47-51(1977) 2.Brindley, P.J., Kalinna, B.H., Dalton, J.P., et al.Proteolytic degradation of host hemoglobin by schistosomesMol. Biochem. Parasitol.89(1)1-9(1997)
