Melicopine
An acridone alkaloid with antimalarial and anticancer activities
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包装价格促销价数量
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1mg￥2800.002240.00- +
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5mg￥9012.007210.00- +
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- 货号: ajcx24588
- CAS: 568-01-4
- 别名:
- 分子式: C17H15NO5
- 分子量: 313.3
- 纯度: ＞98%
- 溶解度:
- 储存: -20°C
- 库存: 现货
Background
Melicopine is an acridone alkaloid that has been found in Z. simulans and has antimalarial and anticancer activities.1 It is active against the chloroquine-sensitive 3D7 and chloroquine-resistant Dd2 strains of P. falciparum with IC50 values of 29.7 and 33.7 µg/ml, respectively. Melicopine is cytotoxic to PC-3M and LNCaP prostate cancer, but not non-cancerous HEK293, cells (IC50s = 47.9, 37.8, and >100 µg/ml, respectively).
1.Wang, C., Wan, J., Mei, Z., et al.Acridone alkaloids with cytotoxic and antimalarial activities from Zanthoxylum simullans HancePharmacogn. Mag.10(37)73-76(2014)
