Adenosine 3’-monophosphate (sodium salt hydrate)

A nucleotide

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
50mg

￥712.00

570.00

- +
100mg

￥1287.00

1030.00

- +
250mg

￥3087.00

2470.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

Background

Adenosine 3’-monophosphate is a nucleotide and metabolite formed via hydrolysis of 2’,3’-cAMP by metal-dependent phosphodiesterases.¹ It reduces proliferation of rat preglomerular vascular smooth muscles cells (PGVSMCs) and glomerular mesangial cells (GMCs) in a concentration-dependent manner, an effect that is abolished by the adenosine A_2B receptor antagonist MRS1754.² Adenosine 3’-monophosphate is also a metabolic intermediate in the biosynthesis of adenosine .

1.Rao, F., Yaning, Q., Murugan, E., et al.20,30-cAMP hydrolysis bymetal-dependent phosphodiesterases containing DHH, EAL, and HD domains is non-specific: Implications for PDE screeningBiochem. Bioph. Res. Commun.398(3)500-505(2010) 2.Jackson, E.K., Gillespie, D.G., and Dubey, R.K.2’-AMP and 3’-AMP inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptorsJ. Pharmacol. Exp. Ther.337(2)444-450(2011)