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- ALK (Anaplastic lymphoma kinase)
- Altemicidin
Altemicidin
A monoterpene alkaloid with acaricidal and anticancer activities
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包装价格促销价数量
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1mg￥9550.007640.00- +
- 货号: ajcx25070
- CAS: 125399-82-8
- 别名: (-)-Altemicidin
- 分子式: C13H20N4O7S
- 分子量: 376.4
- 纯度: ＞98%
- 溶解度: Ethanol: soluble
- 储存: -20°C
- 库存: 现货
Background
Altemicidin is a monoterpene alkaloid originally isolated from S. sioyaensis with acaricidal and anticancer activities.1 It is acaricidal to two-spotted spider mites (T. urticae) in a greenhouse pot test at concentrations of 10 and 100 ppm. Altemicidin inhibits the growth of murine L1210 lymphocytic leukemia and IMC carcinoma cells (IC50s = 0.84 and 0.82 µg/ml, respectively). It is toxic to mice with an LD50 value of 0.3 mg/kg.
1.Takahashi, A., Kurasawa, S., Ikeda, D., et al.Altemicidin, a new acaricidal and antitumor substance. I. Taxonomy, fermentation, isolation and physico-chemical and biological propertiesJ. Antibiot. (Tokyo)42(11)1556-1561(1989)
