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  • Tribenoside
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Tribenoside

A vasoprotective agent

原价
¥600-4475
价格
480-3580
Tribenoside的二维码

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  • 库存: 现货
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  • 货号: ajcx25122
  • CAS: 10310-32-4
  • 别名: 三苄糖甙
  • 分子式: C29H34O6
  • 分子量: 478.6
  • 纯度: >98%
  • 溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
  • 储存: -20°C
  • 库存: 现货

Background

Tribenoside is a vasoprotective agent with anti-allergic and anti-inflammatory activities.1,2 It inhibits agonist-induced contractions in various isolated porcine venous preparations when used at concentrations ranging from 10 to 30 µg/ml.1 Tribenoside inhibits compound 48/80-induced histamine release in isolated rat peritoneal cells (EC50 = 10 µg/ml).3 It reduces decreases in proteoglycan levels and the severity of cartilage destruction in the inflamed joints in a rabbit model of surgically induced osteoarthritis when administered at doses of 100 and 200 mg/kg per day.4 Formulations containing tribenoside have been used in the treatment of hemorrhoids and varicose veins.



1.Jaques, R.The activity pattern, in isolated veins, of a benzyl glucofuranoside derivative possessing combined anti-inflammatory and venotropic effectsPharmacology4(4)193-202(1970) 2.Jaques, R.The pharmacological activity of tribenosidePharmacology15(5)445-460(1977) 3.Rüegg, M., and Jaques, R.Tribenoside as an inhibitor of chemically induced histamine releaseExperientia30(4)399-401(1974) 4.Colombo, C., Butler, M., Hickman, L., et al.A new model of osteoarthritis in rabbits. II. Evaluation of anti-osteoarthritic effects of selected antirheumatic drugs administered systemicallyArthritis Rheum.26(9)1132-1139(1983)

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