Tribenoside

A vasoprotective agent

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
50mg

￥600.00

480.00

- +
100mg

￥1087.00

870.00

- +
250mg

￥2400.00

1920.00

- +
500mg

￥4475.00

3580.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajcx25122
CAS: 10310-32-4
别名: 三苄糖甙
分子式: C29H34O6
分子量: 478.6
纯度: >98%
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
储存: -20°C
库存: 现货

Background

Tribenoside is a vasoprotective agent with anti-allergic and anti-inflammatory activities.^1,2 It inhibits agonist-induced contractions in various isolated porcine venous preparations when used at concentrations ranging from 10 to 30 µg/ml.¹ Tribenoside inhibits compound 48/80-induced histamine release in isolated rat peritoneal cells (EC₅₀ = 10 µg/ml).³ It reduces decreases in proteoglycan levels and the severity of cartilage destruction in the inflamed joints in a rabbit model of surgically induced osteoarthritis when administered at doses of 100 and 200 mg/kg per day.⁴ Formulations containing tribenoside have been used in the treatment of hemorrhoids and varicose veins.

1.Jaques, R.The activity pattern, in isolated veins, of a benzyl glucofuranoside derivative possessing combined anti-inflammatory and venotropic effectsPharmacology4(4)193-202(1970) 2.Jaques, R.The pharmacological activity of tribenosidePharmacology15(5)445-460(1977) 3.Rüegg, M., and Jaques, R.Tribenoside as an inhibitor of chemically induced histamine releaseExperientia30(4)399-401(1974) 4.Colombo, C., Butler, M., Hickman, L., et al.A new model of osteoarthritis in rabbits. II. Evaluation of anti-osteoarthritic effects of selected antirheumatic drugs administered systemicallyArthritis Rheum.26(9)1132-1139(1983)