CAY10781

An NRP-1/VEGF-A interaction inhibitor

原价

￥1012-17437

价格

￥ 810-13950

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库存: 现货

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产品引用

货号: ajcx25166
CAS: 1210360-87-4
别名:
分子式: C11H9N3O3
分子量: 231.2
纯度: >98%
溶解度: DMF: insol,DMSO: 10 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
储存: -20°C
库存: 现货

Background

CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.¹ It inhibits the interaction by 43% when used at a concentration of 12.5 µM. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration.

1.Perez-Miller, S., Patek, M., Moutal, A., et al.In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike proteinbioRxiv308783(2020)

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生命科学

有机化学

无机化学

材料科学

CAY10781

CAY10781详情

Background