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  • Z-FR-AMC (trifluoroacetate salt)
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Z-FR-AMC (trifluoroacetate salt)

A fluorogenic substrate for cathepsin L

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Z-FR-AMC (trifluoroacetate salt)的二维码
  • 库存: 现货
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  • 包装
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  • 10mg
    ¥1012.00
    810.00
    - +
  • 25mg
    ¥2400.00
    1920.00
    - +
  • 50mg
    ¥4525.00
    3620.00
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  • 货号: ajcx25268
  • CAS: N/A
  • 别名: Z-FR-7-amino-4-Methylcoumarin, Z-Phe-Arg-AMC
  • 分子式: C33H36N6O6·XCF3COOH
  • 分子量: 612.7
  • 纯度: >98%
  • 溶解度: DMF: 1 mg/ml,DMSO: 1 mg/ml,Ethanol: 1 mg/ml
  • 储存: -20°C
  • 库存: 现货

Background

Z-FR-AMC is a fluorogenic substrate for cathepsin L.1 Upon enzymatic cleavage by cathepsin L, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin L activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.



1.Carmona, C., Dowd, A.J., Smith, A.M., et al.Cathepsin L proteinase secreted by Fasciola hepatica in vitro prevents antibody-mediated eosinophil attachment to newly excysted juvenilesMol. Biochem. Parasitol.62(1)9-17(1993)

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