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- Acetyl-CoA carboxylase (ACC)
- 16α-hydroxy Dehydroepiandrosterone
16α-hydroxy Dehydroepiandrosterone
A metabolite of dehydroepiandrosterone
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包装价格促销价数量
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1mg￥1012.00810.00- +
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5mg￥4525.003620.00- +
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10mg￥8050.006440.00- +
- 货号: ajcx25298
- CAS: 1232-73-1
- 别名: 16α-hydroxy DHEA
- 分子式: C19H28O3
- 分子量: 304.4
- 纯度: ＞98%
- 溶解度: Chloroform: 10mg/ml
- 储存: -20°C
- 库存: 现货
Background
16α-hydroxy Dehydroepiandrosterone is a metabolite of the endogenous steroid hormone dehydroepiandrosterone .1 16α-hydroxy Dehydroepiandrosterone is formed from dehydroepiandrosterone via 16-hydroxylation by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 in adult human liver microsomes, as well as by fetal recombinant CYP3A7. It is a precursor to fetal estrogens, including estriol .2
1.Miller, K.K.M., Cai, J., Ripp, S.L., et al.Stereo- and regioselectivity account for the diversity of dehydroepiandrosterone (DHEA) metabolites produced by liver microsomal cytochromes P450Drug. Metab. Dispos.32(3)305-313(2004) 2.Hampl, R., and Starka, L.Minireview: 16α-Hydroxylated metabolites of dehydroepiandrosterone and their biological significanceEndocr. Regul.34(3)161-163(2000)
