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- Cyclooxygenase (COX)
- (S)-O-Desmethyl Naproxen
(S)-O-Desmethyl Naproxen
A metabolite of (S)-naproxen
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包装价格促销价数量
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5mg￥2037.001630.00- +
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10mg￥3862.003090.00- +
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25mg￥9162.007330.00- +
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- 货号: ajcx25332
- CAS: 52079-10-4
- 别名: 萘普生杂质A
- 分子式: C13H12O3
- 分子量: 216.2
- 纯度: ＞98%
- 溶解度: DMSO: soluble
- 储存: -20°C
- 库存: 现货
Background
(S)-O-Desmethyl naproxen is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (+)-naproxen ((S)-naproxen; It is formed from (S)-naproxen by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2C9.
1.Miners, J.O., Soulter, S., Tukey, R.H., et al.Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxenBiochem. Pharmacol.51(8)1003-1008(1996)
