4’-hydroxy Trazodone

A metabolite of trazodone

原价

￥4900-4900

价格

￥ 3920-3920

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库存: 现货

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产品引用

货号: ajcx25470
CAS: 53818-10-3
别名:
分子式: C19H22ClN5O2
分子量: 387.9
纯度: >98%
溶解度: Chloroform: slightly soluble,Methanol: slightly, sonicated
储存: -20°C
库存: 现货

Background

4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone.¹ It is an inhibitor of organic anion transporter 3 (OAT3; K_i = 16.9 µM) and is selective for OAT3 over OAT1 (K_i = >200 µM).²

1.Yamato, C., Takahashi, T., Fujita, T., et al.Studies on metabolism of trazodone, II. Metabolic fate after intravenous administration and effects on liver microsomal drug-metabolizing enzymes in ratsXenobiotica4(12)765-777(1974) 2.Zou, L., Matsson, P., Stecula, A., et al.Drug metabolites potently inhibit renal organic anion transporters, OAT1 and OAT3J. Pharm. Sci.110(1)347-353(2021)

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生命科学

有机化学

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4’-hydroxy Trazodone

4’-hydroxy Trazodone详情

Background