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A metabolite of dolutegravir
Dolutegravir M1 is a metabolite of the HIV integrase inhibitor dolutegravir .1 It is formed primarily by the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1B1.
1.Zhu, J., Wang, P., Li, F., et al.CYP1A1 and 1B1-mediated metabolic pathways of dolutegravir, an HIV integrase inhibitorBiochem. Pharmacol.158174-184(2018)
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