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- L-Arginine-d7 (hydrochloride)
L-Arginine-d7 (hydrochloride)
An internal standard for the quantification of L-arginine
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包装价格促销价数量
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1mg￥937.00750.00- +
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5mg￥3262.002610.00- +
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10mg￥5537.004430.00- +
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25mg￥11562.009250.00- +
- 货号: ajcx25704
- CAS: 204244-77-9
- 别名: L-精氨酸D7盐酸盐,(S)-(+)-Arginine-d7 hydrochloride
- 分子式: C6H7D7N4O2·HCl
- 分子量: 217.7
- 纯度: ＞98%
- 溶解度: Water: soluble
- 储存: -20°C
- 库存: 现货
Background
L-Arginine-d7 is intended for use as an internal standard for the quantification of L-arginine by GC- or LC-MS. L-Arginine is an amino acid and a precursor of nitric oxide (NO).1 L-Arginine is a substrate for NO synthase that is oxidized to form NO and L-citrulline. It enhances NO release induced by bradykinin or A23187 in porcine aortic endothelial cells.2 L-Arginine (30 and 300 mg/kg, i.v.) induces dilation of pial arterioles and increases cerebral blood flow in normotensive and spontaneously hypertensive rats.3 It also reduces infarct size by 35 and 28% in normotensive and spontaneously hypertensive rats, respectively, following middle cerebral artery occlusion.
1.Stuehr, D.J.Enzymes of the L-arginine to nitric oxide pathwayJ. Nutr.134(10 Suppl)2748S-2751S(2004) 2.Palmer, R.M.J., Ashton, D.S., and Moncada, S.Vascular endothelial cells synthesize nitric oxide from L-arginineNature333(6174)664-666(1988) 3.Morikawa, E., Moskowitz, M.A., Huang, Z., et al.L-arginine infusion promotes nitric oxide-dependent vasodilation, increases regional cerebral blood flow, and reduces infarction volume in the ratStroke25(2)429-435(1994)
