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  • L-Arginine-d7 (hydrochloride)
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L-Arginine-d7 (hydrochloride)

An internal standard for the quantification of L-arginine

原价
¥937-11562
价格
750-9250
L-Arginine-d7 (hydrochloride)的二维码

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  • 货号: ajcx25704
  • CAS: 204244-77-9
  • 别名: L-精氨酸D7盐酸盐,(S)-(+)-Arginine-d7 hydrochloride
  • 分子式: C6H7D7N4O2·HCl
  • 分子量: 217.7
  • 纯度: >98%
  • 溶解度: Water: soluble
  • 储存: -20°C
  • 库存: 现货

Background

L-Arginine-d7 is intended for use as an internal standard for the quantification of L-arginine by GC- or LC-MS. L-Arginine is an amino acid and a precursor of nitric oxide (NO).1 L-Arginine is a substrate for NO synthase that is oxidized to form NO and L-citrulline. It enhances NO release induced by bradykinin or A23187 in porcine aortic endothelial cells.2 L-Arginine (30 and 300 mg/kg, i.v.) induces dilation of pial arterioles and increases cerebral blood flow in normotensive and spontaneously hypertensive rats.3 It also reduces infarct size by 35 and 28% in normotensive and spontaneously hypertensive rats, respectively, following middle cerebral artery occlusion.



1.Stuehr, D.J.Enzymes of the L-arginine to nitric oxide pathwayJ. Nutr.134(10 Suppl)2748S-2751S(2004) 2.Palmer, R.M.J., Ashton, D.S., and Moncada, S.Vascular endothelial cells synthesize nitric oxide from L-arginineNature333(6174)664-666(1988) 3.Morikawa, E., Moskowitz, M.A., Huang, Z., et al.L-arginine infusion promotes nitric oxide-dependent vasodilation, increases regional cerebral blood flow, and reduces infarction volume in the ratStroke25(2)429-435(1994)

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