A fluorescently labeled form of dATP
Fluorescein-12-dATP is a fluorescently labeled form of the nucleotide 2’-deoxyadenosine-5’-triphosphate . It displays excitation/emission maxima of 498/517 nm, respectively. Fluorescein-12-dATP has been used to label DNA in fluorescence in situ hybridization (FISH) and nicking enzyme-assisted viewing and sequencing (NicE-viewSeq) applications.1,2
1.Estève, P.-O., Vishnu, U.S., Chin, H.G., et al.Visualization and sequencing of accessible chromatin reveals cell cycle and PostHDAC inhibitor treatment dynamicsJ. Mol. Biol.432(19)5304-5321(2020) 2.Kasahara, K., Taguchi, T., Yamasaki, I., et al.Genetic alterations in prostate cancerHandbook of immunohistochemistry and in situ hybridization of human carcinomas, Volume 2: Molecular pathology, colorectal carcinoma, and prostate carcinoma2299-305(2005)
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