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- Dopamine Receptor
- (+/-)-PPCC oxalate
(+/-)-PPCC oxalate
Selective sigma (σ) agonist (σ1> σ2)
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
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包装价格促销价数量
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10mg￥3600.002880.00- +
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50mg￥15087.0012070.00- +
- 货号: ajcx26822
- CAS: 932736-91-9
- 别名:
- 分子式: C24H29NO3.C2H2O4
- 分子量: 469.53
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
Selective sigma (σ) receptor ligand. Displays high affinity for σ1; also binds at σ2 sites (Ki = 1.5 nM and 50.8 nM respectively). Selective over a range of receptor types including dopaminergic and muscarinic receptors, DAT and SERT.
Prezzavento et al (2007) Novel sigma receptor ligands: synthesis and biological profile. J.Med.Chem. 50 951 PMID:17328523 |Prezzavento et al (2008) A new sigma ligand, (±)-PPCC, antagonizes kappa opioid receptor-mediated antinociceptive effect. Life Sci. 82 549 PMID:18261749 |Antonini et al (2009) Anti-amnesic properties of (±)-PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats. J.Neurochem. 109 744 PMID:19245662
