Potent and selective fluorescent adenosine A1 agonist
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High affinity and selective fluorescent adenosine A1 receptor agonist (Ki values are 27, 3600 and 4300 nM for A1, A3 and A2 receptors, respectively). Permits visualization of A1 receptors in the rat cerebellar cortex.
Macchia et al (1998) Fluorescent probes for adenosine receptors: synthesis and biology of N6-dansylaminoalkyl-substituted NECA derivatives. Bioorg. Med. Chem. Lett. 8 3223 PMID:9873707 |Kozma et al (2013) Fluorescent ligands for adenosine receptors. Bioorg. Med. Chem. Lett. 23 26 PMID:23200243
5'-(N-Cyclopropyl)carboxamidoadenosine
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