- 首页
- Ribosomal S6 Kinase (RSK)
- RMM 46
RMM 46
An inhibitor of RSK2
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
-
包装价格促销价数量
-
10mg￥3925.003140.00- +
-
50mg￥16387.0013110.00- +
已选
0
种
0
瓶
金额:
￥0.00
首页
收藏
- 货号: ajcx27294
- CAS: 1307896-46-3
- 别名:
- 分子式: C24H26N4O5
- 分子量: 450.5
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
MSK/RSK family kinase inhibitor. Exhibits selectivity for RSK2 over NEK2 and PLK1 (IC50s are 12, 530 and 2200 nM, respectively). Inhibits MSK1, MSK2, RSK2 and RSK3 in cellular assays. Reduces CREB phosphorylation in HeLa cells.
Miller et al (2013) Electrophilic fragment-based design of reversible covalent kinase inhibitors. J.Am.Chem.Soc. 135 5298 PMID:23540679
