R-BC154
High affinity fluorescent a4 beta 1/a9 beta 1 inhibitor; mobilizes HSCs
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包装价格促销价数量
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1mg￥8125.006500.00- +
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- 货号: ajcx27352
- CAS: N/A
- 别名:
- 分子式: C55H61N9O13S3.CH3CO2H
- 分子量: 1212.37
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
High affinity fluorescent α4β1/α9β1 inhibitor (Kd values are 12.7 and 38 nM, respectively); fluorescent version of BOP (Cat.No. 6047). Rapidly and preferentially mobilizes HSCs and progenitors in vivo. Excitation maximum, 561 nm; emissiosn maximum, 585 nm.
Cao et al (2014) Design, synthesis and binding properties of a fluorescent α9β1/α4β1 integrin antagonist and its application as an in vi Org.Biomol.Chem. 12 965 PMID:24363056 |Cao et al (2016) Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonist. Nat.Commun. 7 11007 PMID:26975966
