AMP PNP

AMP PNP (Adenylyl-imidodiphosphate tetralithium) 是一种不可水解的 ATP 类似物，可抑制 KATP 通道。

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库存: 现货

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1mg

￥637.00

510.00

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5mg

￥1937.00

1550.00

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10mg

￥3425.00

2740.00

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货号: ajcx27368
CAS: 72957-42-7
别名: 腺苷-5'-(Β,Γ-亚氨基)三磷酸四锂,Adenylyl imidodiphosphate
分子式: C10H13Li4N6O12P3
分子量: 529.93
纯度: >98%
溶解度: 26.5mg/ml in water
储存: Store at -20°C
库存: 现货

Background

Non-hydrolyzable AMP analog. Kir6 (KATP) channel blocker. Inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules.
不可水解的AMP类似物。Kir6 (KATP)通道阻滞剂。抑制快速轴索运输并稳定膜质颗粒与微管的相互作用。

参考文献:
[1].Brady (1985) A novel brain ATPase with properties expected for the fast axonal transport motor. Nature 317 73 PMID:2412134.
[2].Yount et al (1971) Adenylyl imidodiphosphate, an adenosine triphosphate analog containing a P-N-P linkage. Biochemistry 10 2484 PMID:4326768.
[3].Hehl and Neumcke (1994) KATP channels of mouse skeletal muscle: mechanism of channel blockage by AMP-PNP. Eur.Biophys.J. 23 231 PMID:7805625.