Thalidomide 4'-oxyacetamide-PEG3-amine

Thalidomide 4'-oxyacetamide-PEG3-amine 是一种合成的 E3 连接酶配体-接头偶联物，它包含用于 PROTAC 技术的基于 Thalidomide 的 cereblon 配体和 3 单元 PEG 接头。

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

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数量
25mg

￥1462.00

1170.00

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已选 0 种 0 瓶

金额: ￥0.00

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Background

Functionalized cereblon ligand for PROTACsup>? research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 1 PROTAC? is a registered trademark of Arvinas Operations, Inc., and is used under license.

Winter et al (2015) Functionalized Cereblon ligand for PROTACs; incorporates an E3 ligase ligand and a linker used in PROTAC technology. Science 348 1376 PMID:25999370 |Salami et al (2017) Waste disposal-An attractive strategy for cancer therapy. Science 355 1163 PMID:28302825