- 首页
- Ligand for Target Protein for PROTAC
- Thalidomide 4'-oxyacetamide-PEG4-amine
Thalidomide 4'-oxyacetamide-PEG4-amine
Thalidomide 4'-oxyacetamide-PEG4-amine 是一种合成的 E3 连接酶配体-接头偶联物，包含基于 Thalidomide 的 cereblon 配体和接头，可用于 PROTAC 的合成。
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
-
包装价格促销价数量
-
25mg￥1762.001410.00- +
- 货号: ajcx27608
- CAS: 2245697-85-0
- 别名:
- 分子式: C25H34N4O10.HCl
- 分子量: 587.02
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
Functionalized cereblon ligand for PROTAC? research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 2 PROTAC? is a registered trademark of Arvinas Operations, Inc., and is used under license.
Winter et al (2015) Drug development. Phthalimide conjugation as a strategy for in vivo target protein degradation. Science 348 1376 PMID:25999370 |Salami et al (2017) Waste disposal-An attractive strategy for cancer therapy. Science 355 1163 PMID:28302825
