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- Ligand for Target Protein for PROTAC
- Thalidomide 4'-oxyacetamide-alkylC4-amine
Thalidomide 4'-oxyacetamide-alkylC4-amine
Thalidomide 4'-oxyetamide-alkylC4-amine 是一种合成的 E3 连接酶配体-接头偶联物，包含基于 Thalidomide 的 cereblon 配体和接头，可用于 PROTAC 的合成。
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
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包装价格促销价数量
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25mg￥1462.001170.00- +
- 货号: ajcx27610
- CAS: 2245697-86-1
- 别名:
- 分子式: C19H22N4O6.HCl
- 分子量: 438.86
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
Functionalized cereblon ligand for PROTAC? research and development; incorporates an E3 ligase ligand plus a short alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 3 PROTAC? is a registered trademark of Arvinas Operations, Inc., and is used under license.
Winter et al (2015) Drug development. Phthalimide conjugation as a strategy for in vivo target protein degradation. Science 348 1376 PMID:25999370 |Salami et al (2017) Waste disposal-An attractive strategy for cancer therapy. Science 355 1163 PMID:28302825
