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- PD-1/PD-L1
- (D)-PPA 1
(D)-PPA 1
An inhibitor of the PD-1-PD-L1 protein-protein interaction
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1mg￥4200.003360.00- +
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- 货号: ajcx27646
- CAS: 1620813-53-7
- 别名:
- 分子式: C70H98N20O21
- 分子量: 1555.67
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
PD-1/PD-L1 interaction inhibitor. Binds to PD-L1 (Kd = 0.51 μM). Inhibits interaction at 1 mg/mL in flow cytometry. Inhibits tumor growth and prolongs survival time of mice in vivo.
Chang et al (2015) Blocking of the PD-1/PD-L1 interaction by a D-peptide antagonist for cancer immunotherapy. Angew Chem.Int.Ed.Engl. 54 11760 PMID:26259671
