High affinity anti-human EGFR aptamer conjugated to Janelia Fluor® 646
High affinity anti-human EGFR aptamer conjugated to Janelia Fluor® 646 (Kd = 0.62 nM). Exhibits high affinity and specificity for human epidermal growth factor receptor (EGFR). Displays dense labeling of the stained structures. Suitable for use in super-resolution microscopy techniques. For optimal binding, aptamers require refolding into their tertiary structure prior to use. Please refer to the protocol for information regarding refolding.
Kim et al (2014) Efficient isolation and elution of cellular proteins using aptamer-mediated protein precipitation assay. Biochem.Biophys.Res.Commun. 448 114 PMID:24768638 |Gomes de Castro et al (2017) Aptamers provide superior stainings of cellular receptors studied under super-resolution microscopy. Send to 12 e0173050 PMID:28235049
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