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  • Thalidomide 4'-ether-alkylC6-amine
Thalidomide 4'-ether-alkylC6-amine的可视化放大

Thalidomide 4'-ether-alkylC6-amine

Thalidomide 4'-ether-alkylC6-amine 是一种合成的 E3 连接酶配体-接头偶联物,用于 PROTAC dTAG-13,FKBP12F36V 和 BET 的降解剂。

原价
¥2712-2712
价格
2170-2170
Thalidomide 4'-ether-alkylC6-amine的二维码

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  • 货号: ajcx27734
  • CAS: 2245697-88-3
  • 别名:
  • 分子式: C19H23N3O5.HCl
  • 分子量: 409.86
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: 4°C, protect from light
  • 库存: 现货

Background

Functionalized cereblon ligand for PROTAC? research and development; incorporates an E3 ligase ligand plus a C6 alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTACs R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 4 PROTAC? is a registered trademark of Arvinas Operations, Inc., and is used under license.



Nabet et al (2018) The dTAG system for immediate and target-specific protein degradation. Nat.Chem.Biol. 14 431 PMID:29581585 |Erb et al (2017) Transcription control by the ENL YEATS domain in acute leukaemia. Nature. 543 270 PMID:28241139

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