Pomalidomide 4'-PEG3-acid

Pomalidomide 4'-PEG3-acid 是一种合成的 E3 连接酶配体-接头偶联物，它包含基于 Thalidomide 的 cereblon 配体和用于 PROTAC 技术的 3 单元 PEG 接头。

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

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数量
25mg

￥2200.00

1760.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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Background

Functionalized cereblon ligand for PROTAC? research and development; incorporates an E3 ligase ligand plus a PEG3 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Pomalidomide - linker 2 PROTAC? is a registered trademark of Arvinas Operations, Inc., and is used under license.

Remillard et al (2017) Degradation of the BAF complex factor BRD9 by heterobifunctional ligands. Angew.Chem.Int.Ed.Engl. 56 5738 PMID:28418626