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- Histone Methyltransferase
- MRK 740
MRK 740
Potent PRDM9 inhibitor
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
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5mg￥1587.001270.00- +
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- 货号: ajcx27826
- CAS: 2387510-80-5
- 别名:
- 分子式: C25H32N6O3
- 分子量: 464.56
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
Potent PRDM9 histone methyltransferase inhibitor (IC50 = 85 nM for in vitro methylation of H3K4). Displays >100-fold selectivity over other histone methyltransferases. Inhibits H3K4 methylation in cells (IC50 = 0.8 μM).
Allali-Hassani et al (2019) Discovery of a chemical probe for PRDM9. Nat.Commun. 10 5759 PMID:31848333
