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VH 032 amide-alkylC2-amine 包含一个用于 E3 泛素连接酶的 VHL 配体和一个 PROTAC 接头。 (S,R,S)-AHPC-OH 可用于合成一系列 PROTAC。
Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC? research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 7 PROTAC? is a registered trademark of Arvinas Operations, Inc., and is used under license.
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