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- Ligand for Target Protein for PROTAC
- VH 032, phenol
VH 032, phenol
VH 032，苯酚是基于 VH032 的 VHL 配体。 VH 032，苯酚可以通过接头连接到蛋白质的配体上，形成PROTAC。
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
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50mg￥7875.006300.00- +
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- 货号: ajcx27888
- CAS: 2244684-42-0
- 别名:
- 分子式: C24H32N4O5S
- 分子量: 488.6
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC? research and development; incorporates an E3 ligase ligand with terminal hydroxyl ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC? is a registered trademark of Arvinas Operations, Inc., and is used under license.
Maniaci et al (2017) Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat.Comm. 8 830 PMID:29018234
