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Derivative of the von Hippel-Lindau (VHL) ligand, VH 032; commonly used as a precursor to a PROTAC? that hijacks VHL as the E3 ubiquitin ligase component
Derivative of the von Hippel-Lindau (VHL) ligand, VH 032; commonly used as a precursor to a PROTAC? that hijacks VHL as the E3 ubiquitin ligase component. Supplied with a primary amine functional handle at a position known not to significantly affect binding to VHL, for ready conjugation to a linker/target protein ligand. PROTAC? is a registered trademark of Arvinas Operations, Inc., and is used under license. Require a different derivative? Get in touch
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