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  • Azido-PEG7-amine
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Azido-PEG7-amine

A heterobifunctional PEGylated linker

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Azido-PEG7-amine的二维码
  • 库存: 现货
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  • 100mg
    ¥837.00
    670.00
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  • 250mg
    ¥1362.00
    1090.00
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  • 货号: ajcx29156
  • CAS: 1333154-77-0
  • 别名: 氨基-七聚乙二醇-叠氮
  • 分子式: C16H34N4O7
  • 分子量: 394.46
  • 纯度: >98%
  • 溶解度: DMSO: 10mg/mL,PBS (pH 7.2): 1mg/mL
  • 储存: -20°C, protect from light
  • 库存: 现货

Background

Azido-dPEG7-amine is a heterobifunctional PEGylated linker.1 It contains a reactive NH2 end group, as well as an azide functional group for use in click chemistry reactions. Azido-dPEG7-amine has been used as a linker in the synthesis of bivalent mammalian target of rapamycin (mTOR) inhibitors.2


1.Goswami, L.N., Houston, Z.H., Sarma, S.J., et al.Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug deliveryOrg. Biomol. Chem.11(7)116-1126(2012) 2.Rodrik-Outmezguine, V.S., Okaniwa, M., Yao, Z., et al.Overcoming mTOR resistance mutations with a new-generation mTOR inhibitorNature534(7606)272-276(2016)

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