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- m-PEG-Succinimidyl Succinate (MW 5000)
m-PEG-Succinimidyl Succinate (MW 5000)
m-PEG-Succinimidyl Succinate (MW 5000) 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。
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包装价格促销价数量
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100mg￥3100.002480.00- +
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250mg￥4962.003970.00- +
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- 货号: ajcx29518
- CAS: N/A
- 别名:
- 分子式:
- 分子量: 5000(Average)
- 纯度: ＞98%
- 溶解度:
- 储存: Store at -20°C
- 库存: 现货
Background
m-PEG-Succinimidyl Succinate (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
