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  3. SIRT7 inhibitor 97491
  • SIRT7 inhibitor 97491
SIRT7 inhibitor 97491的可视化放大

SIRT7 inhibitor 97491

SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 i

原价
￥1100-12050
价格
￥ 880-9640
SIRT7 inhibitor 97491的二维码

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  • 库存: 现货
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  • 货号: ajcx29684
  • CAS: 1807758-81-1
  • 别名:
  • 分子式: C15H12ClN3O
  • 分子量: 285.73
  • 纯度: >98%
  • 溶解度: DMSO :57 mg/mL(199.48 mM; Moisture absorption of DMSO will reduce the solubility of the compound, please use newly opened DMSO)
  • 储存: 4°C, protect from light
  • 库存: 现货

Background

SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.


[1] Kim JH, et al. Biochem Biophys Res Commun. 2019 Jan 8;508(2):451-457.

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