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  • Tromantadine hydrochloride
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Tromantadine hydrochloride

Tromantadine hydrochloride,Amantadine 衍生物,具有抗疱疹活性,可抑制单纯疱疹病毒1型 (HSV-1) 和 HSV-2 的复制。

原价
¥3775-27250
价格
3020-21800
Tromantadine hydrochloride的二维码

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  • 库存: 现货
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  • 货号: ajcx29752
  • CAS: 41544-24-5
  • 别名:
  • 分子式: C16H29ClN2O2
  • 分子量: 316.87
  • 纯度: >98%
  • 溶解度:
  • 储存: Store at 2-8°C
  • 库存: 现货

Background

Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication[1].


Treatment of the cells with 10 to 50μg of Tromantadine reduces HSV-induced cytopathic effect. Treatment with 100 to 500μg of Tromantadine inhibits herpes simplex virus-induced cytopathic effect and reduces virus production. Complete inhibition of virus production is observed with treatments of 500μg to 1 mg. The antiherpetic activity of Tromantadine is dependent upon the viral inoculum size and the time of addition of the compound with respect to infection[1].


[1]. Rosenthal KS, et al. Tromantadine: inhibitor of early and late events in herpes simplex virus replication. Antimicrob Agents Chemother. 1982 Dec;22(6):1031-6.

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