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(S)-Venlafaxine是Venlafaxine的S构型化合物。Venlafaxine是口服有效的5-羟色胺(5-HT)/去甲肾上腺素(NE)重摄取的双重抑制剂。Venlafaxine具有抗抑郁作用。
(S)-Venlafaxine is the (S)-configuration of Venlafaxine. Venlafaxine is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant agent[1].
[1]. Bymaster FP, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.
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