6''-O-Acetylsaikosaponin A

6''-O-AcetylsaikosaponinA，从柴胡根中分离得到的乙酰柴胡皂苷，具有一定的破骨细胞抑制活性。

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Background

6''-O-Acetylsaikosaponin A, an acetyl saikosaponin isolated from the roots of Bupleurum chinense, shows some osteoclast-inhibiting activities[1].

The major bioactive compounds isolated from R. bupleuri are saikosaponins, which have been proved to possess significant biological activities, including anti-hepatitis, anti-inflammatory, anti-tumor and immunoregulatory effects[2].

[1]. Yu JQ, et al. Osteoclast-inhibiting saikosaponin derivatives from Bupleurum chinense. Fitoterapia. 2013;85:101-108. [2]. Huang HQ, et al. Fast determination of saikosaponins in Bupleurum by rapid resolution liquid chromatography with evaporative light scattering detection. J Pharm Biomed Anal. 2009;49(4):1048-1055.