7-Prenyloxyaromadendrin

7-Prenyloxyaromadendrin是一种来自Pterocaulonalopecuroides的类黄酮，具有抗肿瘤活性。7-Penyloxyaromadendrin在肿瘤细胞系中显示出良好的抗增殖活性。

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Background

7-Prenyloxyaromadendrin is a flavonoid from Pterocaulon alopecuroides with antitumor activity. 7-Prenyloxyaromadendrin shows good antiproliferative activity in tumor cell lines[1][2].

7-Prenyloxyaromadendrin (compound 5) shows antiproliferative activity with GI50 values in the range 16-20 μM in A549, HBL-100, HeLa, SW1573, T-47D cells[2]. 7-Prenyloxyaromadendrin (compound 5) is inactive on B. subtilis and B. cereus (there is no zone of inhibition at the concentration of 50 μg/disk)[1].

[1]. Rosana Alarcón, et al. Flavonoids from Pterocaulon alopecuroides with antibacterial activity. Planta Med. 2008 Oct;74(12):1463-7. [2]. Quírico A Castillo, et al. Secondary Metabolites from Pterocaulon alopecuroides and their Antiproliferative Activities. Pharmacognosy Journal,2019,11,3,493-495.