BDTX-189
An inhibitor of wild-type and mutant EGFR and HER2
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
-
包装价格促销价数量
-
5mg￥762.00610.00- +
-
10mg￥1300.001040.00- +
-
25mg￥2725.002180.00- +
-
50mg￥4850.003880.00- +
-
100mg￥8100.006480.00- +
已选
0
种
0
瓶
金额:
￥0.00
首页
收藏
- 货号: ajcx30248
- CAS: 2414572-47-5
- 别名: BDTX-189
- 分子式: C29H29ClN6O4
- 分子量: 561.03
- 纯度: ＞98%
- 溶解度:
- 储存: Store at -20°C
- 库存: 现货
Background
BDTX-189 is an inhibitor of wild-type and mutant EGFR and HER2 (IC50s = ≤30-500 and ≤10-100 nM, respectively).1 In vivo, BDTX-189 (30 and 50 mg/kg, twice daily) reduces tumor growth in a CUTO14 non-small cell lung cancer (NSCLC) mouse xenograft model.
1.Flohr, A., Mayweg, A., Trainor, G., et al.Quinazoline derivatives as tyrosine kinase inhibitor, compositions, methods of making them and their use(2020)
