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  • Boc-NH-PEG3-CH2COOH
Boc-NH-PEG3-CH2COOH的可视化放大

Boc-NH-PEG3-CH2COOH

A building block

原价
¥437-437
价格
350-350
Boc-NH-PEG3-CH2COOH的二维码

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  • 货号: ajcx30298
  • CAS: 462100-06-7
  • 别名: 5,8,11-三氧杂-2-氮杂十三烷二酸1-叔丁酯
  • 分子式: C13H25NO7
  • 分子量: 307.34
  • 纯度: >98%
  • 溶解度: DMF: 5 mg/ml,DMSO: 1 mg/ml,Ethanol: 30 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Boc-NH-PEG3-CH2COOH is a building block.1,2 It has been used as a linker in the synthesis of proteolysis-targeting chimeras (PROTACs) targeting MEK.1 It has also been used as a spacer in the synthesis of radiolabeled probes for dual labeling of tumor integrin αVβ3 and the gastrin-releasing peptide receptor (GRPR) in tumor tissue in vivo.2


1.Vollmer, S., Cunoosamy, D., Lv, H., et al.Design, synthesis, and biological evaluation of MEK PROTACsJ. Med. Chem.63(1)157-162(2020) 2.Liu, Z., Yan, Y., Chin, F.T., et al.Dual integrin and gastrin-releasing peptide receptor targeted tumor imaging using 18F-labeled PEGylated RGD-bombesin heterodimer 18F-FB-PEG3-Glu-RGD-BBNJ. Med. Chem.52(2)425-432(2009)

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