DBCO-CONH-S-S-NHS ester

DBCO-CONH-S-S-NHSester是一种可降解(cleavable)的ADClinker，可用于合成抗体偶联药物(ADC)。

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Background

DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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