- 首页
- Angiotensin-converting Enzyme (ACE)
- DBCO-NHCO-PEG12-maleimide
DBCO-NHCO-PEG12-maleimide
DBCO-NHCO-PEG12-maleimide是一种PROTAClinker，属于PEG类。可用于合成PROTAC分子。
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
-
包装价格促销价数量
-
100mg￥17100.0013680.00- +
已选
0
种
0
瓶
金额:
￥0.00
首页
收藏
- 货号: ajcx30466
- CAS: N/A
- 别名:
- 分子式: C52H74N4O17
- 分子量: 1027.16
- 纯度: ＞98%
- 溶解度:
- 储存: Store at -20°C
- 库存: 现货
Background
DBCO-NHCO-PEG12-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
