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- Acetylcholinesterase (AChE or acetylhydrolase)
- Fmoc-Gly3-Val-Cit-PAB
Fmoc-Gly3-Val-Cit-PAB
Fmoc-Gly3-Val-Cit-PAB是一种可降解(cleavable)的ADClinker，可用于合成抗体偶联药物(ADC)。
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包装价格促销价数量
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100mg￥4100.003280.00- +
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500mg￥11875.009500.00- +
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- 货号: ajcx30668
- CAS: 2647914-09-6
- 别名:
- 分子式: C39H48N8O9
- 分子量: 772.85
- 纯度: ＞98%
- 溶解度: DMSO: 100 mg/mL (129.39 mM); Water: < 0.1 mg/mL (insoluble)
- 储存: 4°C, stored under nitroge
- 库存: 现货
Background
Fmoc-Gly3-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
