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  • Ganciclovir sodium
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Ganciclovir sodium

An antiviral drug that is effective against CMV

原价
¥625-962
价格
500-770
Ganciclovir sodium的二维码

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  • 货号: ajcx30698
  • CAS: 107910-75-8
  • 别名: 更昔洛韦钠,BW 759 sodium; 2'-Nor-2'-deoxyguanosine sodium
  • 分子式: C9H14N5NaO4
  • 分子量: 279.23
  • 纯度: >98%
  • 溶解度: Water: 50 mg/mL (179.06 mM); DMSO: 5 mg/mL (17.91 mM)
  • 储存: Store at 4°C, protect from light
  • 库存: 现货

Background

Ganciclovir is a synthetic analog of 2'-deoxy-guanosine which is used to treat or prevent cytomegalovirus (CMV) infections.1,2 It inhibits the replication of human CMV with an IC50 value of 0.01 μM and is effective against strains of CMV from human, monkey, mouse, and guinea pig.3,4


1.Balfour, H.H., Jr.Management of cytomegalovirus disease with antiviral drugsRev. Infect. Dis.12(Suppl. 7)S849-S860(1990) 2.Bean, B.Antiviral therapy: Current concepts and practicesClin. Microbiol. Rev.5(2)146-182(1992) 3.Rasmussen, L., Chen, P.T., Mullenax, J.G., et al.Inhibition of human cytomegalovirus replication by 9-(1,3-dihydroxy-2-propoxymethyl)guanine alone and in combination with human interferonsAntimicrob. Agents Chemother.26(4)441-445(1984) 4.Freitas, V.R., Smee, D.F., Chernow, M., et al.Activity of 9-(1,3-dihydroxy-2-propoxymethyl)guanine compared with that of acyclovir against human, monkey, and rodent cytomegalovirusesAntimicrob. Agents Chemother.28(2)240-245(1985)

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