L-Diguluronic acid

L-Diguluronicacid是一种由两个L-guluronicacid(G)组成的直链多糖共聚物，可用于海藻酸的合成。L-Diguluronicacid是一种无支链聚阴离子多糖的总称，可用于抗真菌(antifungal)试剂的载体研究。

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5mg

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Background

L-Diguluronic acid is a linear polysaccharide copolymer composed of two L-guluronic acid (G) and can be used to from Alginate[1]. Alginate is a generic name of unbranched polyanionic polysaccharides and can be used for the research of antifungal agents delivery carries[2].

Alginate is a generic name assigned to a series of polyanionic polysaccharides of β-d-mannuronic acid (M) and α-l-guluronic acid (G). Alginate is linked by a 1→4 linkage and displaying chain homosequences of MMM and GGG, interdispersed with MGM heterosequences[1].Alginate is widely used for obtainment of drug delivery systems due to its non-toxicity, biodegradability, biocompatibility, mucoadhesive, and non-immunogenic properties. Additionally, alginate-based antifungal delivery systems have great potential in the treatment of fungal infections in vivo[1].

[1]. R.A. Shirwaiker, et al. L-Guluronic Acid [2]. Cristina de Castro Spadari, et al. Potential Use of Alginate-Based Carriers As Antifungal Delivery System.Front Microbiol. 2017 Jan 30;8:97.